- © JKurreck
The department is headed by Prof. Dr. Jens Kurreck
Research in the Department of Applied Biochemistry focusses on
the application of biotechnological methods in molecular medicine. We
aim at elucidating mechanisms of pathogenicity and to develop new
therapeutic approaches. To this end, we use RNA technologies such as
RNA intereference or CRISPR/Cas9 to specifically silence the
expression of genes. Our group recently identified a small interfering
RNA (siRNA) which inhibits the SARS-coronavirus-2 with high efficiency
and is now developed further.
Furthermore, we contribute to animal welfare by developing new
replacement models for animal experiments. Three-dimensional
bioprinting produces organ models which can be used for infection
studies. This strategy also has the advantage to produce humanized
models which may have a greater relevance for the understanding of
human diseases than animal models.
Further projects develop oncolytic viruses that inhibit the growth
of tumors and the development of metastasis. In addition, RNA
technologies are used to inhibit pathogenic viral infections.
On Science and Arts: The Melody of the Genome  is a musical
journal through the human DNA (in German).
Fon 030 314 27581
Fax 030 314 27502
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